StemPar Sciences Secures Initial Funding For Its Novel Cancer Metabolism Drugs
San Francisco, CA, Jan. 2, 2013 (GLOBE NEWSWIRE) -- Privately held StemPar Sciences, Inc. today announced an initial investment from Troika Venture Capital, a multi-profile international venture capital firm. In addition, Troika has committed to participate in future StemPar financings.
StemPar is an industry leader in cancer metabolism, rapidly advancing a DNQ-derived small molecule aimed at an equally novel drug target--a protein called NQO1--for pancreatic, breast and lung cancers.StemPar est un leader dans le domaine du métabolisme du cancer, avançant rapidement vers un nouveau médicament ciblant une protéine appelée NQO1 qui joue un rôle dans le cancer du , du et du
Cancer treatments in development have been moving increasingly toward targeted therapies with much improved patient selection using specific biomarkers. Targeted therapies like StemPar's drug candidates represent the potential to overcome many of the limitations of currently available cancer drugs. StemPar's lead drug is targeting NQO1, which is found at high levels in pancreatic, breast and lung cancers. StemPar is also developing companion diagnostic tests to detect the NQO1 target protein with the aim of significantly improving the ability to determine which patients are most likely to respond to this therapy because of their specific genetic makeup.La compagnie développe aussi un test pour savoir qui bénéficiera le plus du médeicament
The Company's leadership team has a solid track record of developing innovative, commercially valuable cancer drugs. StemPar co-founder, President & CEO Barry Sherman, MD is a biotech visionary who has long been at the forefront of innovative cancer drug development, most recently at BiPar Sciences, which was ultimately acquired by Sanofi-Aventis. As Genentech's first Chief Medical Officer, Dr. Sherman played a significant role in the development of a number of breakthrough drugs that have generated billions of dollars of revenues and touched the lives of millions of patients. StemPar cofounder and Chairman Hoyoung Huh, MD, PhD was CEO at BiPar. Dr. Huh has engineered some of the most successful turnarounds and trade sale exits in biotech and pharma. He now serves on a number of boards at leading public and private global biotech firms.
"We are extremely pleased to be working with the very committed and talented team at Troika," said StemPar CEO Barry Sherman. "They recognize commercially valuable science, IP and paradigm-shifting market potential when they see them. At the same time, they understand that one of the best ways to mitigate the risk that so often comes with early stage opportunities with breakthrough potential is to build their investment around an experienced management team like ours, which has deep roots in breakthrough cancer care innovation."
"We think that StemPar has great potential to advance cancer care," said Artyom Yukhin, managing director at Troika. "Because of the dislocation that the US venture capital industry is currently going through, we see an interesting opportunity to match global pools of investment capital with exciting technologies like StemPar."Nous pensons que StemPar a un grand potentiel pour faire avancer les soins en oncologie.
StemPar's Scientific Advisory Team includes recognized authorities on cancer metabolism, DNA repair, the NQO1-mediated cell death pathway, and the DNQ small molecule. David Boothman, Ph.D. is Professor & Associate Director of Translational Research at the University of Texas-Southwestern Medical Center. Prof. Boothman is a recognized authority on cancer metabolism and DNA repair. His work over two decades, which began at Harvard University Medical Center and the Dana-Farber Cancer Inst., has elucidated the NQO1 pathway as a novel target for cancer therapeutics. Paul Hergenrother, Ph.D. is Professor of Chemistry at the University of Illinois at Urbana-Champaign. He is a leader in the field of chemical biology.